含氮雜環(huán)化合物的合成、結(jié)構(gòu)、生物活性、熱力學(xué)、熱行為及量子化學(xué)研究.pdf

1、分類號(hào)：一一一密級(jí)：?jiǎn)挝淮a：!!!!!學(xué)號(hào)：200410121西北大學(xué)博士學(xué)位論文題目：金氫盤堡垡金塹鮑全盛!繾撿!生塑適：睦!墊左堂14指導(dǎo)教師：塞絲鎣專業(yè)技術(shù)職務(wù)：教授學(xué)科(專業(yè))：垡堂王壁答辯日期_!魚(yú)!!!i學(xué)位授予日期：二00七年五月AbstractAsenesofheterocyclicnitrogencompoundsI一ⅫI：NmethylacylN(pymidin2y1)thiourea；II：NethylacylN

2、(pymidin一2一y1)thiourea；]II：Nbenzoyl—N(pymidin2y1)thiourea；IV：NmethoxylacylN(4，6dimethxoylpymidin2y1)thiourea；V：NethoxylacytN(4。6dimethxoylpymidin2y1)thiourea=Ⅵ：NbenzoyIN(4，6dimethxoyl—pymidin2一y1)thiourea；V1]：Nmethoxylac

3、ylN(1，2。4triazole5one2y1)thiourea；NethoxylacylN(1，2，4tdazole5one2叫)thiourea：Ⅸ：N—benzoyIN(1，2，4tnazole5one2yI)thiourea；X：NmethoxylacylN‘《4，6dimethyl—pymidin一2叫)thiourea；X[：Nethoxylacyi—NL(4。6dimethylpyrimidin2y1)thiourea；

4、Ⅻ：NbenzoyI—N(4，6一dimethylpyrimidin2yi)thiourea，weresynthesizedwithcombinatorialchemistrymethodtakingpynmidineandtriazolecompoundscontainingnitrogenheterocyclesasaleadcompound，andisothiocyanateasamod行yinggroupTheirstructu

5、reshavebeenconfirmedbyelementalanalysisandFTIRAnewimidazolederivationwithnitrogenheterocyclic，2methyl3但，4dichlorobenzyl)5一nitrylimidazole(MNI)，wassynthesizedwithanaloguesynthesismethodanddeterminedbyIRandelementalanalysi

6、sAnewmetalcomplexwaspreparedanditssinglecrystalstructurewasdeterminedThedissolvablecapabilityofthecompoundsIo皿inorganicsolvent：cycloexylamine，nheptane。benzene。toluene，1，2dichloroethane，chloroform，dichloromethane，methanol

7、。ethanol，propano!，nbutylalcohol，nitromethane。acetonitdle。formamide，dimethylformamide，1，4dioxane，tetrahydrofuran。dimethylsulfoxidewerestudiedThesinglecrystalsofthecompoundsI。II，V，Ⅵ，IXandMNlwereobtainedbyslowevaporationofa

8、solventatroomtemperatureforthefirsttimeandtheircrystalstructureweredeterminedwithaXraydiffractometerThebioactivityofthecompoundsI，II’Ⅲ。V，ViandⅨwerestudiedbymicrobeofGibberellanico婦ncolaandAppleblackfruitrotandtheeffectso